Life Science Research Professional II
Company: Stanford Medicine
Location: Castro Valley
Posted on: May 16, 2022
The Division of Infectious Diseases and Geographic Medicine ,
within Stanford University, Department of Medicine is seeking a
Life Science Research Professional II to perform more complex
functions and activities involved in defined research projects, and
independently conduct a portion of the research project(s).
Studies in our lab are driven by the hypothesis that IgG repertoire
diversity is a central driver of heterogeneity in human immune
functioning and susceptibility to diseases. We are specifically
interested in diversity that exists in the Fc domain repertoire
among people, which we define by serum IgG subclass and Fc
glycoform distributions. We have found that the Fc domain
repertoire of an individual impacts key immune processes such as
vaccine responses and susceptibility to antibody-dependent
enhancement of dengue disease (Wang TT, Cell. 2015 and Wang TT,
Science. 2017). This is because IgG subclasses and Fc glycoforms
dictate the structure of Fc domains within immune complexes that
form during vaccination or infection. This, in turn, determines the
affinity of immune complexes for various Fc receptors on effector
cells. Thus, our research seeks to define how the Fc domain
repertoire of an individual determines the quality of effector cell
responses that can be recruited during immune activation.
- Independently conduct a portion of the research project(s).
Make recommendations on experimental design and/or research
direction to principal investigator.
- Independently conduct complex (lab and/or field) experiments to
gather data for a portion of a major research project.
- Interpret and analyze results, often where few guidelines
exist, and make modifications to existing procedures and
- Develop new research protocols where appropriate protocols are
not described in the literature or where modification or adaptation
of standard procedures and protocols is required.
- Participate in multidisciplinary teams across different
faculties or schools.
- Perform ongoing literature review to remain current with new
procedures and related research; apply to ongoing research and
development of new protocols.
- Contribute substantively to the preparation of papers for
publication, especially in the results section, and to publication
of findings. Present ongoing work to colleagues and/or academic
- Oversee supply and equipment budget under supervision of
principal investigator or business manager.
- Work with health and safety department to ensure lab complies
with regulations and all required trainings.
- Supervise (either formally or informally) staff or students as
needed, including oversight and direction on techniques, as well as
consultation on project work. Serve as a technical resource for
other research staff.
- Oversee the daily activities of the laboratory including lab
maintenance; maintain lab stock, manage chemical inventory and
safety records, and provide general lab support as needed. May
assist with purchasing laboratory equipment.
The job duties listed are typical examples of work performed by
positions in this job classification and are not designed to
contain or be interpreted as a comprehensive inventory of all
duties, tasks, and responsibilities. Specific duties and
responsibilities may vary depending on department or program needs
without changing the general nature and scope of the job or level
of responsibility. Employees may also perform other duties as
- A Master's degree in biology, immunology, biochemistry,
bioengineering, molecular biology or related field.
- Experience and proficiency with basic methods of molecular
biology (PCR, cloning, Western blots), cell culture and experience
with in vivo systems will be important for this position.
- 5+ years laboratory experience, or equivalent.
- Proficiency in cloning and protein production.
- Experience with mouse models of virus infection including
malaria, influenza and/or dengue.
- Experience with scientific writing.
- Experience with tissue culture-based virus growth, titer
assays, and neutralization assays.
EDUCATION & EXPERIENCE (REQUIRED):
- Bachelor's degree in related scientific field and two years of
relevant work experience; or Master's degree in a related
KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
- Comprehensive understanding of scientific principles.
- General computer skills and ability to quickly learn and master
computer programs, databases, and scientific applications.
- Strong analytical skills and excellent judgment.
- Ability to maintain detailed records of experiments and
- Ability to work under deadlines with general guidance is
- Excellent organizational skills and demonstrated ability to
accurately complete detailed work.
- Frequently stand, walk, twist, bend, stoop, squat, grasp
lightly, use fine manipulation, grasp forcefully, perform
desk-based computer tasks, use telephone, write by hand, lift,
carry, push and pull objects weighing over 40 pounds.
- Occasionally sit, kneel, crawl, reach and work above shoulders,
sort and file paperwork or parts.
- Rarely climb, scrub, sweep, mop, chop and mix or operate hand
and foot controls.
- Must have correctible vision to perform duties of the job.
- Ability to bend, squat, kneel, stand, reach above shoulder
level, and move on hard surfaces for up to eight hours.
- Ability to lift heavy objects weighing up to 50 pounds.
- Ability to work in a dusty, dirty, and odorous
- Position may require repetitive motion.
Consistent with its obligations under the law, the University will
provide reasonable accommodation to any employee with a disability
who requires accommodation to perform the essential functions of
his or her job.
- May require working in close proximity to blood borne
- May require work in an environment where animals are used for
teaching and research.
- Position may at times require the employee to work with or be
in areas where hazardous materials and/or infectious diseases are
- Employee must perform tasks that require the use of personal
protective equipment, such as safety glasses and shoes, protective
clothing and gloves, and possibly a respirator.
- May require extended or unusual work hours based on research
requirements and business needs.
- Interpersonal Skills: Demonstrates the ability to work well
with Stanford colleagues and clients and with external
- Promote Culture of Safety: Demonstrates commitment to personal
responsibility and value for safety; communicates safety concerns;
uses and promotes safe behaviors bases on training and lessons
- Subject to and expected to comply with all applicable
University policies and procedures, including but not limited to
the personnel policies and other policies found in the University's
Administrative Guide, .
Why Stanford is for You
Imagine a world without search engines or social platforms.
Consider lives saved through first-ever organ transplants and
research to cure illnesses. Stanford University has revolutionized
the way we live and enrich the world. Supporting this mission is
our diverse and dedicated 17,000 staff. We seek talent driven to
impact the future of our legacy. Our culture and unique perks
empower you with:
- Freedom to grow. We offer career development programs, tuition
reimbursement, or audit a course. Join a TedTalk, film screening,
or listen to a renowned author or global leader speak.
- A caring culture. We provide superb retirement plans, generous
time-off, and family care resources.
- A healthier you. Climb our rock wall, or choose from hundreds
of health or fitness classes at our world-class exercise
facilities. We also provide excellent health care benefits.
- Discovery and fun. Stroll through historic sculptures, trails,
- Enviable resources. Enjoy free commuter programs, ridesharing
incentives, discounts and more.
Stanford is an equal employment opportunity and affirmative action
employer. All qualified applicants will receive consideration for
employment without regard to race, color, religion, sex, sexual
orientation, gender identity, national origin, disability,
protected veteran status, or any other characteristic protected by
As an organization that receives federal funding, Stanford
University has a COVID-19 vaccination requirement that will apply
to all university employees, including those working remotely in
the United States and applicable subcontractors. To learn more
about COVID policies and guidelines for Stanford University Staff,
please visit .
- Schedule: Full-time
- Job Code: 4952
- Employee Status: Regular
- Pay Grade: G
- Requisition ID: 92250 As an organization that receives federal
funding, Stanford University has a COVID-19 vaccination requirement
that will apply to all university employees, including those
working remotely in the United States and applicable
subcontractors. To learn more about COVID policies and guidelines
for Stanford University Staff, please visit
Keywords: Stanford Medicine, Castro Valley , Life Science Research Professional II, Other , Castro Valley, California
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